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Hydrophobic Surface Burial is the Major Stability Determinant of a Flat, Single-Layer β-Sheet

Formation of a flat β-sheet is a fundamental event in β-sheet-mediated protein self-assembly. To investigate contributions of various factors to the stability of flat β-sheets, we performed extensive alanine-scanning mutagenesis experiments on the single-layer β-sheet segment of Borrelia outer surfa...

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Main Authors: Yan, Shude, Gawlak, Grzegorz, Makabe, Koki, Tereshko, Valentina, Koide, Akiko, Koide, Shohei
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1995161/
https://ncbi.nlm.nih.gov/pubmed/17335845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.02.003
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