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Hydrophobic Surface Burial is the Major Stability Determinant of a Flat, Single-Layer β-Sheet
Formation of a flat β-sheet is a fundamental event in β-sheet-mediated protein self-assembly. To investigate contributions of various factors to the stability of flat β-sheets, we performed extensive alanine-scanning mutagenesis experiments on the single-layer β-sheet segment of Borrelia outer surfa...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1995161/ https://ncbi.nlm.nih.gov/pubmed/17335845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.02.003 |
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