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Atomic-resolution crystal structure of Borrelia burgdorferi outer surface protein A via surface engineering
Outer surface protein A (OspA) from Borrelia burgdorferi has an unusual dumbbell-shaped structure in which two globular domains are connected with a “single-layer” β-sheet (SLB). The protein is highly soluble, and it has been recalcitrant to crystallization. Only OspA complexes with Fab fragments ha...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2242579/ https://ncbi.nlm.nih.gov/pubmed/16823038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062246706 |
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