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β-Strand Flipping and Slipping Triggered by Turn Replacement Reveal the Opportunistic Nature of β-Strand Pairing

We investigated how the register between adjacent β-strands is specified using a series of mutants of the single-layer β-sheet (SLB) in Borrelia OspA. The single-layer architecture of this system eliminates structural restraints imposed by a hydrophobic core, enabling us to address this question. A...

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Autori principali: Makabe, Koki, Yan, Shude, Tereshko, Valentina, Gawlak, Grzegorz, Koide, Shohei
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596595/
https://ncbi.nlm.nih.gov/pubmed/17985889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja074252c
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