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Promotion of Tubulin Assembly by Poorly Soluble Taxol Analogs
Promotion or inhibition of tubulin assembly into microtubules is the standard in vitro assay for evaluating potential antimicrotubule agents. Many agents to be tested are poorly soluble in aqueous solution and require a cosolvent such as DMSO4. However, DMSO itself can promote tubulin assembly, and...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1868410/ https://ncbi.nlm.nih.gov/pubmed/17097592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2006.10.01 |
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