Posttranslational Acetylation of the Human Immunodeficiency Virus Type 1 Integrase Carboxyl-Terminal Domain Is Dispensable for Viral Replication

A recent report sought to demonstrate that acetylation of specific lysines within integrase (IN) by the histone acetyltransferase (HAT) p300 regulates human immunodeficiency virus type 1 (HIV-1) integration and is essential for viral replication (A. Cereseto, L. Manganaro, M. I. Gutierrez, M. Terren...

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Hlavní autoři: Topper, Michael, Luo, Yang, Zhadina, Maria, Mohammed, Kevin, Smith, Leonard, Muesing, Mark A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2007
Témata:
Genome Replication and Regulation of Viral Gene Expression
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865993/
https://ncbi.nlm.nih.gov/pubmed/17182677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02257-06
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