Genetic Analyses of Conserved Residues in the Carboxyl-Terminal Domain of Human Immunodeficiency Virus Type 1 Integrase

Results of in vitro assays identified residues in the C-terminal domain (CTD) of human immunodeficiency virus type 1 (HIV-1) integrase (IN) important for IN-IN and IN-DNA interactions, but the potential roles of these residues in virus replication were mostly unknown. Sixteen CTD residues were targe...

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Detalhes bibliográficos
Main Authors: Lu, Richard, Ghory, Hina Z., Engelman, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182625/
https://ncbi.nlm.nih.gov/pubmed/16051828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.16.10356-10368.2005
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