Lys-34, Dispensable for Integrase Catalysis, Is Required for Preintegration Complex Function and Human Immunodeficiency Virus Type 1 Replication

Retroviral integrases (INs) function in the context of preintegration complexes (PICs). Two conserved Lys residues in the N-terminal domain of human immunodeficiency virus type 1 (HIV-1) IN were analyzed here for their roles in integration and virus replication. Whereas HIV-1(K46A) grew like the wil...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Lu, Richard, Vandegraaff, Nick, Cherepanov, Peter, Engelman, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1211547/
https://ncbi.nlm.nih.gov/pubmed/16160186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.19.12584-12591.2005
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados