Recombinant Human Immunodeficiency Virus Type 1 Integrase Exhibits a Capacity for Full-Site Integration In Vitro That Is Comparable to That of Purified Preintegration Complexes from Virus-Infected Cells

Retrovirus preintegration complexes (PIC) in virus-infected cells contain the linear viral DNA genome (∼10 kbp), viral proteins including integrase (IN), and cellular proteins. After transport of the PIC into the nucleus, IN catalyzes the concerted insertion of the two viral DNA ends into the host c...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Sinha, Sapna, Grandgenett, Duane P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1143728/
https://ncbi.nlm.nih.gov/pubmed/15956566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.13.8208-8216.2005
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados