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The Foamy Virus Genome Remains Unintegrated in the Nuclei of G(1)/S Phase-Arrested Cells, and Integrase Is Critical for Preintegration Complex Transport into the Nucleus

Foamy viruses are a member of the spumavirus subfamily of retroviruses with unique mechanisms of virus replication. Foamy virus replication is cell cycle dependent; however, the genome is found in the nuclei of cells arrested in the G(1)/S phase. Despite the presence of genome in the nuclei of growt...

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Autores principales: Lo, Yung-Tsun, Tian, Tao, Nadeau, Peter E., Park, Jeonghae, Mergia, Ayalew
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826029/
https://ncbi.nlm.nih.gov/pubmed/20032182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02435-09
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