Caveolin-1 Modulates HIV-1 Envelope-Induced Bystander Apoptosis through gp41

Human immunodeficiency virus (HIV) envelope (Env)-mediated bystander apoptosis is known to cause the progressive, severe, and irreversible loss of CD4(+) T cells in HIV-1-infected patients. Env-induced bystander apoptosis has been shown to be gp41 dependent and related to the membrane hemifusion bet...

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Bibliographic Details
Main Authors: Wang, Xiao Mei, Nadeau, Peter E., Lo, Yung-Tsun, Mergia, Ayalew
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903242/
https://ncbi.nlm.nih.gov/pubmed/20392844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02722-09
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