Efficient Concerted Integration by Recombinant Human Immunodeficiency Virus Type 1 Integrase without Cellular or Viral Cofactors

Replication of retroviruses requires integration of the linear viral DNA genome into the host chromosomes. Integration requires the viral integrase (IN), located in high-molecular-weight nucleoprotein complexes termed preintegration complexes (PIC). The PIC inserts the two viral DNA termini in a con...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Sinha, Sapna, Pursley, Michael H., Grandgenett, Duane P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136053/
https://ncbi.nlm.nih.gov/pubmed/11884535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.7.3105-3113.2002
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados