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Correlation of Recombinant Integrase Activity and Functional Preintegration Complex Formation during Acute Infection by Replication-Defective Integrase Mutant Human Immunodeficiency Virus

Previous studies characterized two types of replication-defective human immunodeficiency virus type 1 (HIV-1) integrase mutants: class I, which are specifically blocked at the integration step, and class II, which harbor additional virion production and/or reverse transcription defects. Class I muta...

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Detalhes bibliográficos
Main Authors: Li, Xiang, Koh, Yasuhiro, Engelman, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302524/
https://ncbi.nlm.nih.gov/pubmed/22278243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06386-11
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