Impairment of Human Immunodeficiency Virus Type-1 Integrase SUMOylation Correlates with an Early Replication Defect

HIV-1 integrase (IN) orchestrates the integration of the reverse transcribed viral cDNA into the host cell genome and participates also in other steps of HIV-1 replication. Cellular and viral factors assist IN in performing its multiple functions, and post-translational modifications contribute to m...

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Dades bibliogràfiques
Autors principals: Zamborlini, Alessia, Coiffic, Audrey, Beauclair, Guillaume, Delelis, Olivier, Paris, Joris, Koh, Yashuiro, Magne, Fabian, Giron, Marie-Lou, Tobaly-Tapiero, Joelle, Deprez, Eric, Emiliani, Stephane, Engelman, Alan, de Thé, Hugues, Saïb, Ali
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
Matèries:
Microbiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121452/
https://ncbi.nlm.nih.gov/pubmed/21454548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.189274
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