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Sequential Deletion of the Integrase (Gag-Pol) Carboxyl Terminus Reveals Distinct Phenotypic Classes of Defective HIV-1

A requisite step in the life cycle of human immunodeficiency virus type 1 (HIV-1) is the insertion of the viral genome into that of the host cell, a process catalyzed by the 288-amino-acid (32-kDa) viral integrase (IN). IN recognizes and cleaves the ends of reverse-transcribed viral DNA and directs...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mohammed, Kevin D., Topper, Michael B., Muesing, Mark A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126176/
https://ncbi.nlm.nih.gov/pubmed/21367893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02374-10
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