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A Premature Termination Codon Mutation at the C Terminus of Foamy Virus Gag Downregulates the Levels of Spliced pol mRNA

Foamy viruses (FV) comprise a subfamily of retroviruses. Orthoretroviruses, such as human immunodeficiency virus type 1, synthesize Gag and Pol from unspliced genomic RNA. However, FV Pol is expressed from a spliced mRNA independently of Gag. FV pol splicing uses a 3′ splice site located at the 3′ e...

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Detalhes bibliográficos
Main Authors: Lee, Eun-Gyung, Kuppers, Daniel, Horn, Megan, Roy, Jacqueline, May, Cynthia, Linial, Maxine L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258731/
https://ncbi.nlm.nih.gov/pubmed/18057244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00990-07
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