Characterization of in vitro and in vivo hypomethylating effects of decitabine in acute myeloid leukemia by a rapid, specific and sensitive LC-MS/MS method

DNA hypermethylation is a common finding in malignant cells and has been explored as a therapeutic target for hypomethylating agents (e.g., decitabine). Detection of changes in DNA methylation might serve as a pharmacodynamic endpoint to establish the biological activity of these agents and predict...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Liu, Zhongfa, Liu, Shujun, Xie, Zhiliang, Blum, William, Perrotti, Danilo, Paschka, Peter, Klisovic, Rebecca, Byrd, John, Chan, Kenneth K., Marcucci, Guido
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2007
נושאים:
Methods Online
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865075/
https://ncbi.nlm.nih.gov/pubmed/17264127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl1156
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים