A LC-MS/MS Method for the Analysis of Intracellular Nucleoside Triphosphate Levels

PURPOSE: To simultaneously quantify intracellular nucleoside triphosphate (NTP) and deoxynucleoside triphosphate (dNTP) pools and to assess their changes produced by interfering with ribonucleotide reductase (RNR) expression in leukemia cells. METHODS: A HPLC-MS/MS system was used to quantify intrac...

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Detalhes bibliográficos
Main Authors: Chen, Ping, Liu, Zhongfa, Liu, Shujun, Xie, Zhiliang, Aimiuwu, Josephine, Pang, Jiuxia, Klisovic, Rebecca, Blum, William, Grever, Michael R., Marcucci, Guido, Chan, Kenneth K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071250/
https://ncbi.nlm.nih.gov/pubmed/19291372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-009-9863-9
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