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Determination of intracellular fludarabine triphosphate in human peripheral blood mononuclear cells by LC-MS/MS

Fludarabine is a nucleoside analog routinely used in conditioning regimens of pediatric allogeneic stem cell transplantation to promote stem cell engraftment. In children, it remains a challenge to accurately and precisely quantify the active intracellular triphosphate species of fludarabine in vivo...

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Detalhes bibliográficos
Main Authors: Huang, Liusheng, Lizak, Patricia, Aweeka, Francesca, Long-Boyle, Janel
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835489/
https://ncbi.nlm.nih.gov/pubmed/24013121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2013.08.007
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