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The von Hippel–Lindau tumor suppressor gene is required for cell cycle exit upon serum withdrawal

The inactivation of the von Hippel–Lindau (VHL) tumor suppressor gene predisposes affected individuals to the human VHL cancer syndrome and is associated with sporadic renal cell carcinomas (RCC) and brain hemangioblastomas. VHL-negative 786–0 RCC cells are tumorigenic in nude mice which is suppress...

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Detaylı Bibliyografya
Asıl Yazarlar: Pause, Arnim, Lee, Stephen, Lonergan, Kim M., Klausner, Richard D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 1998
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC18649/
https://ncbi.nlm.nih.gov/pubmed/9448273
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