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Nuclear/cytoplasmic localization of the von Hippel-Lindau tumor suppressor gene product is determined by cell density.

The product of the von Hippel-Lindau (VHL) tumor suppressor gene, the gene inactivated in VHL disease and in sporadic clear-cell renal carcinomas, has recently been shown to have as a functional target the transcription elongation complex, elongin (also called SIII). Here it is shown that there is a...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Lee, S, Chen, D Y, Humphrey, J S, Gnarra, J R, Linehan, W M, Klausner, R D
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39856/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8700833/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.5.1770
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