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The von Hippel–Lindau tumor suppressor gene is required for cell cycle exit upon serum withdrawal

The inactivation of the von Hippel–Lindau (VHL) tumor suppressor gene predisposes affected individuals to the human VHL cancer syndrome and is associated with sporadic renal cell carcinomas (RCC) and brain hemangioblastomas. VHL-negative 786–0 RCC cells are tumorigenic in nude mice which is suppress...

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保存先:
書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Pause, Arnim, Lee, Stephen, Lonergan, Kim M., Klausner, Richard D.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 1998
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18649/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9448273/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.3.993
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