FoxOs are lineage-restricted redundant tumor suppressors and critical regulators of endothelial cell homeostasis

Activated phosphoinositide 3-kinase (PI3K)-AKT signalling appears to be an obligate event in the development of cancer. The highly related members of the mammalian FoxO transcription factor family, FoxO1, FoxO3 and FoxO4, represent one of several effector arms of PI3K-AKT signalling, prompting genet...

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書誌詳細
主要な著者: Paik, Ji-Hye, Kollipara, Ramya, Chu, Gerald, Ji, Hongkai, Xiao, Yonghong, Ding, Zhihu, Miao, Lili, Tothova, Zuzana, Horner, James W., Carrasco, Daniel R., Jiang, Shan, Gilliland, D. Gary, Chin, Lynda, Wong, Wing H., Castrillon, Diego H., DePinho, Ronald A.
フォーマット: Artigo
言語:Inglês
出版事項: 2007
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855089/
https://ncbi.nlm.nih.gov/pubmed/17254969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2006.12.029
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