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Subcellular localization of Grb2 by the adaptor protein Dok-3 restricts the intensity of Ca(2+) signaling in B cells
Spatial and temporal modulation of intracellular Ca(2+) fluxes controls the cellular response of B lymphocytes to antigen stimulation. Herein, we identify the hematopoietic adaptor protein Dok-3 (downstream of kinase-3) as a key component of negative feedback regulation in Ca(2+) signaling from the...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1852829/ https://ncbi.nlm.nih.gov/pubmed/17290227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601557 |
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