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CBFB-MYH11 hinders early T-cell development and induces massive cell death in the thymus
Recent studies suggest that the chromosome 16 inversion, associated with acute myeloid leukemia M4Eo, takes place in hematopoietic stem cells. If this is the case, it is of interest to know the effects of the resulting fusion gene, CBFB-MYH11, on other lineages. Here we studied T-cell development in...
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| Huvudupphovsmän: | , , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society of Hematology
2007
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1852246/ https://ncbi.nlm.nih.gov/pubmed/17185462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-10-051508 |
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