CBFB-MYH11 hinders early T-cell development and induces massive cell death in the thymus

Recent studies suggest that the chromosome 16 inversion, associated with acute myeloid leukemia M4Eo, takes place in hematopoietic stem cells. If this is the case, it is of interest to know the effects of the resulting fusion gene, CBFB-MYH11, on other lineages. Here we studied T-cell development in...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Zhao, Ling, Cannons, Jennifer L., Anderson, Stacie, Kirby, Martha, Xu, Liping, Castilla, Lucio H., Schwartzberg, Pamela L., Bosselut, Rémy, Liu, P. Paul
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2007
Sujets:
Neoplasia
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852246/
https://ncbi.nlm.nih.gov/pubmed/17185462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-10-051508
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires