CBFB-MYH11 hinders early T-cell development and induces massive cell death in the thymus

Recent studies suggest that the chromosome 16 inversion, associated with acute myeloid leukemia M4Eo, takes place in hematopoietic stem cells. If this is the case, it is of interest to know the effects of the resulting fusion gene, CBFB-MYH11, on other lineages. Here we studied T-cell development in...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Zhao, Ling, Cannons, Jennifer L., Anderson, Stacie, Kirby, Martha, Xu, Liping, Castilla, Lucio H., Schwartzberg, Pamela L., Bosselut, Rémy, Liu, P. Paul
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2007
Ämnen:
Neoplasia
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852246/
https://ncbi.nlm.nih.gov/pubmed/17185462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-10-051508
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk