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What happens in the thymus does not stay in the thymus: how T cells recycle the CD4(+)-CD8(+) lineage commitment transcriptional circuitry to control their function
MHC-restricted CD4(+) and CD8(+) T cell are at the core of most adaptive immune responses. Although these cells carry distinct functions, they arise from a common precursor during thymic differentiation, in a developmental sequence that matches CD4 and CD8 expression and functional potential with MH...
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| Опубликовано в: : | J Immunol |
|---|---|
| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4894541/ https://ncbi.nlm.nih.gov/pubmed/27260768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600415 |
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