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What happens in the thymus does not stay in the thymus: how T cells recycle the CD4(+)-CD8(+) lineage commitment transcriptional circuitry to control their function

MHC-restricted CD4(+) and CD8(+) T cell are at the core of most adaptive immune responses. Although these cells carry distinct functions, they arise from a common precursor during thymic differentiation, in a developmental sequence that matches CD4 and CD8 expression and functional potential with MH...

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Dades bibliogràfiques
Publicat a:J Immunol
Autors principals: Vacchio, Melanie S., Bosselut, Rémy
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4894541/
https://ncbi.nlm.nih.gov/pubmed/27260768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600415
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