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CD4-CD8 differentiation in the thymus: connecting circuits and building memories
The proper choice of the CD4-helper or CD8-cytotoxic lineages by developing T cells is crucial for the generation of an antigen-responsive and functionally fit T cell repertoire. Here we present a brief overview of the transcriptional control of this process, with emphasis on two issues. The study o...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3773541/ https://ncbi.nlm.nih.gov/pubmed/22387323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2012.02.002 |
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