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CD4-CD8 differentiation in the thymus: connecting circuits and building memories

The proper choice of the CD4-helper or CD8-cytotoxic lineages by developing T cells is crucial for the generation of an antigen-responsive and functionally fit T cell repertoire. Here we present a brief overview of the transcriptional control of this process, with emphasis on two issues. The study o...

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Detalhes bibliográficos
Main Authors: Xiong, Yumei, Bosselut, Rémy
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773541/
https://ncbi.nlm.nih.gov/pubmed/22387323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2012.02.002
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