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Maintaining CD4-CD8 lineage integrity in T cells: where plasticity serves versatility

The divergence of the two αβ T cell subsets defined by the mutually exclusive expression of CD4 and CD8 glycoproteins is an important event during the intrathymic differentiation of T lymphocytes. This reviews briefly summarizes the mechanisms that promote commitment to the CD4 or CD8 lineage in the...

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Autors principals: Wang, Lie, Xiong, Yumei, Bosselut, Rémy
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740965/
https://ncbi.nlm.nih.gov/pubmed/21963088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2011.08.008
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