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Expression of the transcription factor cKrox in peripheral CD8 T cells reveals substantial postthymic plasticity in CD4-CD8 lineage differentiation

Most T cells belong to either of two lineages defined by the mutually exclusive expression of CD4 and CD8 coreceptors: CD4 T cells are major histocompatibility complex (MHC) II restricted and have helper function, whereas CD8 T cells are MHC I restricted and have cytotoxic function. The divergence b...

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Detalhes bibliográficos
Main Authors: Jenkinson, S. Rhiannon, Intlekofer, Andrew M., Sun, Guangping, Feigenbaum, Lionel, Reiner, Steven L., Bosselut, Rémy
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118724/
https://ncbi.nlm.nih.gov/pubmed/17296789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20061982
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