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Maintaining CD4-CD8 lineage integrity in T cells: where plasticity serves versatility

The divergence of the two αβ T cell subsets defined by the mutually exclusive expression of CD4 and CD8 glycoproteins is an important event during the intrathymic differentiation of T lymphocytes. This reviews briefly summarizes the mechanisms that promote commitment to the CD4 or CD8 lineage in the...

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Sonraí Bibleagrafaíochta
Main Authors: Wang, Lie, Xiong, Yumei, Bosselut, Rémy
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740965/
https://ncbi.nlm.nih.gov/pubmed/21963088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2011.08.008
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