The transcription factor Ets1 is important for CD4 repression and Runx3 up-regulation during CD8 T cell differentiation in the thymus

The transcription factor Ets1 contributes to the differentiation of CD8 lineage cells in the thymus, but how it does so is not understood. In this study, we demonstrate that Ets1 is required for the proper termination of CD4 expression during the differentiation of major histocompatability class 1 (...

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Bibliographic Details
Main Authors: Zamisch, Monica, Tian, Linhua, Grenningloh, Roland, Xiong, Yumei, Wildt, Kathryn F., Ehlers, Marc, Ho, I-Cheng, Bosselut, Rémy
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806616/
https://ncbi.nlm.nih.gov/pubmed/19917777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20092024
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