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Selective deletion of antigen-specific CD8(+) T cells by MHC class I tetramers coupled to the type I ribosome-inactivating protein saporin
CD8(+) cytotoxic T lymphocytes (CTLs) are important effector cells responsible for tissue destruction in several autoimmune and allograft-related diseases. To discover if pathogenic T cells could be selectively deleted, we investigated the ability of a toxin coupled to major histocompatibility compl...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Hematology
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1852243/ https://ncbi.nlm.nih.gov/pubmed/17179221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-06-028001 |
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