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Population analysis of antiviral T cell responses using MHC class I-peptide tetramers

MHC class I-peptide tetrameric complexes (‘tetramers’) have revolutionized the study of antiviral CD8(+) T cell responses. They allow accurate quantification of immune responses ex vivo independent of function, with high levels of sensitivity. They have revealed unexpectedly large frequencies of ‘me...

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Autors principals: KOMATSU, H, SIERRO, S, CUERO, A V, KLENERMAN, P
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1808834/
https://ncbi.nlm.nih.gov/pubmed/12974748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2003.02266.x
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