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Assessment of CD4(+) and CD8(+) T Cell Responses Using MHC Class I and II Tetramers

The low frequency of T cells specific for given antigens makes the study of antigen-specific T cell responses difficult. The development of MHC class I and II tetramer staining techniques allows precise quantification and tracking of antigen-specific CD8(+) and CD4(+) T cell responses. Here, we desc...

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Publicat a:Methods Mol Biol
Autors principals: Kurtulus, Sema, Hildeman, David
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4265237/
https://ncbi.nlm.nih.gov/pubmed/23397390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-290-2_8
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