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Toxin coupled MHC class I tetramers can specifically ablate autoreactive CD8(+) T cells and delay diabetes in NOD mice

There is compelling evidence that self reactive CD8(+) T cells are a major factor in development and progression of Type 1 diabetes in animals and humans. Hence, great effort has been expended to define the specificity of autoimmune CD8(+) T cells, and to alter their responses. Much work has focused...

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מידע ביבליוגרפי
Main Authors: Vincent, Benjamin G., Young, Ellen F., Buntzman, Adam S., Stevens, Rosemary, Kepler, Thomas B., Tisch, Roland, Frelinger, Jeffrey A., Hess, Paul R.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868268/
https://ncbi.nlm.nih.gov/pubmed/20220085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903931
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