Selective deletion of antigen-specific CD8(+) T cells by MHC class I tetramers coupled to the type I ribosome-inactivating protein saporin

CD8(+) cytotoxic T lymphocytes (CTLs) are important effector cells responsible for tissue destruction in several autoimmune and allograft-related diseases. To discover if pathogenic T cells could be selectively deleted, we investigated the ability of a toxin coupled to major histocompatibility compl...

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Bibliografiske detaljer
Main Authors: Hess, Paul R., Barnes, Carie, Woolard, Matthew D., Johnson, Michael D. L., Cullen, John M., Collins, Edward J., Frelinger, Jeffrey A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2007
Fag:
Immunobiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852243/
https://ncbi.nlm.nih.gov/pubmed/17179221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-06-028001
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