INK4a/ARF Locus Alterations in Human Non-Hodgkin’s Lymphomas Mainly Occur in Tumors with Wild-Type p53 Gene

INK4a/ARF locus codes for two different proteins, p16(INK4a) and p14(ARF), involved in cell cycle regulation. p14(ARF) is considered an upstream regulator of p53 function. To determine the role of these genes in the pathogenesis of human non-Hodgkin’s lymphomas we have analyzed exon 1β, 1α, and 2 of...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Pinyol, Magda, Hernández, Luis, Martínez, Antonio, Cobo, Francesc, Hernández, Silvia, Beà, Silvia, López-Guillermo, Armando, Nayach, Iracema, Palacín, Antonio, Nadal, Alfons, Fernández, Pedro L., Montserrat, Emilio, Cardesa, Antonio, Campo, Elías
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2000
Soggetti:
Regular Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850083/
https://ncbi.nlm.nih.gov/pubmed/10854221
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi