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INK4a/ARF Locus Alterations in Human Non-Hodgkin’s Lymphomas Mainly Occur in Tumors with Wild-Type p53 Gene
INK4a/ARF locus codes for two different proteins, p16(INK4a) and p14(ARF), involved in cell cycle regulation. p14(ARF) is considered an upstream regulator of p53 function. To determine the role of these genes in the pathogenesis of human non-Hodgkin’s lymphomas we have analyzed exon 1β, 1α, and 2 of...
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| Главные авторы: | , , , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Investigative Pathology
2000
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1850083/ https://ncbi.nlm.nih.gov/pubmed/10854221 |
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