INK4a/ARF Locus Alterations in Human Non-Hodgkin’s Lymphomas Mainly Occur in Tumors with Wild-Type p53 Gene

INK4a/ARF locus codes for two different proteins, p16(INK4a) and p14(ARF), involved in cell cycle regulation. p14(ARF) is considered an upstream regulator of p53 function. To determine the role of these genes in the pathogenesis of human non-Hodgkin’s lymphomas we have analyzed exon 1β, 1α, and 2 of...

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Main Authors: Pinyol, Magda, Hernández, Luis, Martínez, Antonio, Cobo, Francesc, Hernández, Silvia, Beà, Silvia, López-Guillermo, Armando, Nayach, Iracema, Palacín, Antonio, Nadal, Alfons, Fernández, Pedro L., Montserrat, Emilio, Cardesa, Antonio, Campo, Elías
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2000
Fag:
Regular Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850083/
https://ncbi.nlm.nih.gov/pubmed/10854221
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