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Epigenetic regulation of the INK4b-ARF-INK4a locus: In sickness and in health
The INK4b-ARF-INK4a locus encodes for two cyclin-dependent kinase inhibitors, p15(INK4b) and p16(INK4a), and a regulator of the p53 pathway, ARF. In addition ANRIL , a non-coding RNA, is also transcribed from the locus. ARF, p15(INK4b) and p16(INK4a) are well-established tumor suppressors which func...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Landes Bioscience
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3052884/ https://ncbi.nlm.nih.gov/pubmed/20716961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.5.8.12996 |
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