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SirT3 is a nuclear NAD(+)-dependent histone deacetylase that translocates to the mitochondria upon cellular stress

In humans, there are at least seven Sir2-like proteins (SirT1–7) with diverse functions, including the regulation of chromatin structure, and metabolism. SirT3 levels have been shown to correlate with extended life span, to localize to the mitochondria, and to be highly expressed in brown adipose ti...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Scher, Michael B., Vaquero, Alejandro, Reinberg, Danny
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1847710/
https://ncbi.nlm.nih.gov/pubmed/17437997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1527307
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