SIRT3, a human SIR2 homologue, is an NAD- dependent deacetylase localized to mitochondria
The SIR2 (silent information regulator 2) gene family has diverse functions in yeast including gene silencing, DNA repair, cell-cycle progression, and chromosome fidelity in meiosis and aging. Human homologues, termed sirtuins, are highly conserved but are of unknown function. We previously identifi...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC129731/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12374852/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.222538099 |
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