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The Conserved Core of a Human SIR2 Homologue Functions in Yeast Silencing

Silencing is a universal form of transcriptional regulation in which regions of the genome are reversibly inactivated by changes in chromatin structure. Sir2 (Silent Information Regulator) protein is unique among the silencing factors in Saccharomyces cerevisiae because it silences the rDNA as well...

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Detalhes bibliográficos
Main Authors: Sherman, Joyce M., Stone, Elisa M., Freeman-Cook, Lisa L., Brachmann, Carrie B., Boeke, Jef D., Pillus, Lorraine
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC25551/
https://ncbi.nlm.nih.gov/pubmed/10473645
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