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An Acetylation Site in the Middle Domain of Hsp90 Regulates Chaperone Function
Heat shock protein 90 (Hsp90) chaperones a key subset of signaling proteins and is necessary for malignant transformation. Hsp90 is subject to an array of post-translational modifications which affect its function, including acetylation. Histone deacetylase (HDAC) inhibitors and knock-down of HDAC6...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1839984/ https://ncbi.nlm.nih.gov/pubmed/17218278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2006.12.008 |
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