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The complex dance of the molecular chaperone Hsp90
Hsp90 chaperone function requires traversal of a nucleotide-dependent conformational cycle, but the slow and variable rate of Hsp90-mediated ATP hydrolysis is difficult to envision as a determinant of conformational change. A recent study solves this dilemma by showing that Hsp90 samples multiple co...
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| Udgivet i: | Trends Biochem Sci |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7282695/ https://ncbi.nlm.nih.gov/pubmed/19359180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2009.01.006 |
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