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Targeting the dynamic HSP90 complex in cancer
The molecular chaperone heat shock protein 90 (HSP90) has been used by cancer cells to facilitate the function of numerous oncoproteins, and it can be argued that cancer cells are ‘addicted’ to HSP90. However, although recent reports of the early clinical efficacy of HSP90 inhibitors are encouraging...
में बचाया:
| में प्रकाशित: | Nat Rev Cancer |
|---|---|
| मुख्य लेखकों: | , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2010
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6778733/ https://ncbi.nlm.nih.gov/pubmed/20651736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc2887 |
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