Загрузка...

Targeting the dynamic HSP90 complex in cancer

The molecular chaperone heat shock protein 90 (HSP90) has been used by cancer cells to facilitate the function of numerous oncoproteins, and it can be argued that cancer cells are ‘addicted’ to HSP90. However, although recent reports of the early clinical efficacy of HSP90 inhibitors are encouraging...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Nat Rev Cancer
Главные авторы: Trepel, Jane, Mollapour, Mehdi, Giaccone, Giuseppe, Neckers, Len
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778733/
https://ncbi.nlm.nih.gov/pubmed/20651736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc2887
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!