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Functioning of the Hsp90 machine in chaperoning checkpoint kinase 1 (Chk1) and the progesterone receptor (PR)

Hsp90 is an abundant and highly conserved chaperone that functions at later stages of protein folding to maintain and regulate the activity of client proteins. Using a recently described in vitro system to fold a functional model kinase Chk1, we performed a side-by-side comparison of the Hsp90-depen...

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Detalhes bibliográficos
Main Authors: Felts, Sara J., Karnitz, Larry M., Toft, David O.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Stress Society International 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2134797/
https://ncbi.nlm.nih.gov/pubmed/18229454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1379/CSC-299.1
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