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Hsp90 molecular chaperone inhibitors: Are we there yet?

Heat shock protein (Hsp) 90 is an ATP-dependent molecular chaperone exploited by malignant cells to support activated oncoproteins, including many cancer-associated kinases and transcription factors, and is essential for oncogenic transformation. Originally viewed with skepticism, Hsp90 inhibitors a...

詳細記述

保存先:
書誌詳細
主要な著者: Neckers, Len, Workman, Paul
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252205/
https://ncbi.nlm.nih.gov/pubmed/22215907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-1000
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