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The double edge of the HSP90–CDC37 chaperone machinery: opposing determinants of kinase stability and activity
The molecular chaperone HSP90, in concert with the co-chaperone CDC37, facilitates the maturation and modulates the activity of a variety of protein kinases. In this article, Gaude and colleagues described the dual activities of the HSP90–CDC37 chaperone machinery in maintaining the stability while...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2012
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3458789/ https://ncbi.nlm.nih.gov/pubmed/22894668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fon.12.80 |
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