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Coordinated Regulation of Serum- and Glucocorticoid-inducible Kinase 3 by a C-terminal Hydrophobic Motif and Hsp90-Cdc37 Chaperone Complex

Serum- and glucocorticoid-inducible kinase 3 (SGK3) mediates a variety of cellular processes including membrane transport, cell proliferation, and survival, and it has been implicated in Akt-independent signaling downstream of oncogenic PIK3CA mutations (activating mutations in the α catalytic subun...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wang, Yuanzhong, Xu, Wanping, Zhou, Dujin, Neckers, Len, Chen, Shiuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931044/
https://ncbi.nlm.nih.gov/pubmed/24379398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.518480
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