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Intersubunit movement is required for ribosomal translocation

Translocation of tRNA and mRNA during protein synthesis is believed to be coupled to structural changes in the ribosome. The “ratchet model,” based on cryo-EM reconstructions of ribosome complexes, invokes relative movement of the 30S and 50S ribosomal subunits in this process; however, evidence tha...

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Bibliografske podrobnosti
Main Authors: Horan, Lucas H., Noller, Harry F.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829233/
https://ncbi.nlm.nih.gov/pubmed/17360328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700762104
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