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Intersubunit movement is required for ribosomal translocation

Translocation of tRNA and mRNA during protein synthesis is believed to be coupled to structural changes in the ribosome. The “ratchet model,” based on cryo-EM reconstructions of ribosome complexes, invokes relative movement of the 30S and 50S ribosomal subunits in this process; however, evidence tha...

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Detalhes bibliográficos
Main Authors: Horan, Lucas H., Noller, Harry F.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829233/
https://ncbi.nlm.nih.gov/pubmed/17360328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700762104
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